CMap Candidate Details

Structure:
CMap ID: C23514
Pert ID: BRD-K66412701
Compound Name: pazufloxacin
Targets: --
MoA: --
SMILES: C[C@H]1COc2c(c(F)cc3c2n1cc(C(O)=O)c3=O)C1(N)CC1
InchiKey: XAGMUUZPGZWTRP-ZETCQYMHSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
25406 BRD-K66412701 VCAP 10 uM 24 h -0.21 -0.89 0.03 0.34 1.2 1.1
91330 BRD-K66412701 HUH7 10 uM 72 h 0.0 0.0 0.0 0.0 0.0 0.0
124945 BRD-K66412701 A375 3.33 uM 24 h 0.0 0.0 0.0 0.31 1.1 0.68
124979 BRD-K66412701 A549 0.125 uM 24 h 0.0 0.0 0.0 -0.3 -1.0 0.52
125008 BRD-K66412701 HA1E 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
125040 BRD-K66412701 HELA 1.11 uM 24 h 0.0 0.0 0.0 -0.32 -1.08 0.79
125059 BRD-K66412701 HT29 10 uM 24 h 0.23 0.95 0.07 0.0 0.0 0.0
125081 BRD-K66412701 MCF10A 0.37 uM 24 h 0.0 0.0 0.0 -0.23 -0.76 0.08
125122 BRD-K66412701 MDAMB231 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
125180 BRD-K66412701 THP1 1.11 uM 24 h 0.0 0.0 0.0 -0.25 -0.85 0.2
133070 BRD-K66412701 HEK293 0.03 uM 24 h 0.0 0.0 0.0 -0.27 -0.92 0.32
133177 BRD-K66412701 JURKAT 0.08 uM 24 h 0.2 0.85 0.01 0.0 0.0 0.0
133239 BRD-K66412701 MCF??7.00 0.01 uM 24 h 0.0 0.0 0.0 -0.2 -0.66 0.01
133299 BRD-K66412701 PC3 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133323 BRD-K66412701 YAPC 0.03 uM 24 h 0.0 0.0 0.0 -0.33 -1.11 0.91
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).