CMap Candidate Details

Structure:
CMap ID: C23634
Pert ID: BRD-K66782112
Compound Name: ICI-162846
Targets: HRH2
MoA: Histamine receptor antagonist
SMILES: NC(=O)CCCCn1ccc(N=C(N)NCC(F)(F)F)n1
InchiKey: ALCSGJCIESECFD-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1604 BRD-K66782112 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
1944 BRD-K66782112 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
2409 BRD-K66782112 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
2670 BRD-K66782112 VCAP 10 uM 6 h -0.32 -1.35 0.98 0.0 0.0 0.0
41824 BRD-K66782112 A375 10 uM 6 h 0.0 0.0 0.0 -0.29 -0.97 0.45
41969 BRD-K66782112 A549 10 uM 24 h -0.22 -0.92 0.06 0.0 0.0 0.0
42438 BRD-K66782112 ASC 10 uM 24 h 0.0 0.0 0.0 0.25 0.9 0.22
42753 BRD-K66782112 HEPG2 10 uM 6 h -0.21 -0.88 0.03 0.0 0.0 0.0
43052 BRD-K66782112 HT29 10 uM 6 h 0.0 0.0 0.0 -0.29 -0.96 0.43
43222 BRD-K66782112 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 -0.36 -1.2 1.17
43618 BRD-K66782112 NPC 10 uM 24 h 0.0 0.0 0.0 -0.35 -1.17 1.13
43919 BRD-K66782112 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
44174 BRD-K66782112 SKB 10 uM 24 h 0.19 0.81 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).