CMap Candidate Details

Structure:
CMap ID: C23636
Pert ID: BRD-K66788707
Compound Name: fludarabine
Targets: RRM1
MoA: DNA synthesis inhibitor
SMILES: Nc1nc(F)nc2n(cnc12)[C@@H]1O[C@H](CO)[C@@H](O)[C@@H]1O
InchiKey: HBUBKKRHXORPQB-FJFJXFQQSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1202 BRD-K66788707 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
1248 BRD-K66788707 A549 10 uM 48 h 0.0 0.0 0.0 -0.18 -0.6 0.0
1290 BRD-K66788707 MCF??7.00 10 uM 48 h 0.0 0.0 0.0 0.25 0.89 0.2
1353 BRD-K66788707 U2OS 10 uM 48 h 0.0 0.0 0.0 -0.22 -0.73 0.05
49876 BRD-K66788707 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
50221 BRD-K66788707 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
50394 BRD-K66788707 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
50570 BRD-K66788707 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
51168 BRD-K66788707 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).