CMap Candidate Details

Structure:
CMap ID: C02365
Pert ID: BRD-A98283014
Compound Name: calmidazolium
Targets: ATP2B1; PDE1A
MoA: Calmodulin antagonist; Calcium channel blocker
SMILES: Clc1ccc(cc1)C(c2ccc(Cl)cc2)[n+]3ccn(CC(OCc4ccc(Cl)cc4Cl)c5ccc(Cl)cc5Cl)c3
InchiKey: CTKNMSVWMRRCPW-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
33884 BRD-A98283014 A549 10 uM 6 h -0.18 -0.74 0.0 0.0 0.0 0.0
34019 BRD-A98283014 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
34534 BRD-A98283014 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
34802 BRD-A98283014 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
35072 BRD-A98283014 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
35287 BRD-A98283014 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
36051 BRD-A98283014 PC3 10 uM 6 h 0.0 0.0 0.0 -0.53 -1.77 15.65
36174 BRD-A98283014 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
36468 BRD-A98283014 SKB 10 uM 24 h 0.0 0.0 0.0 0.33 1.16 0.9
36756 BRD-A98283014 VCAP 10 uM 24 h 0.0 0.0 0.0 -0.34 -1.16 1.1
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).