CMap Candidate Details

Structure:
CMap ID: C23657
Pert ID: BRD-K66847579
Compound Name: WZ-7043
Targets: CSF1R
MoA: CSF1R inhibitor
SMILES: CCN(CC)CCCCNc1ncc2CN(C(=O)N(C)c2n1)c1c(Cl)c(OC)cc(OC)c1Cl
InchiKey: NHOUHWHGHAFDOP-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
91519 BRD-K66847579 BT20 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
91583 BRD-K66847579 HS578T 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
91636 BRD-K66847579 MCF10A 10 uM 6 h 0.0 0.0 0.0 0.32 1.14 0.85
91662 BRD-K66847579 MCF??7.00 10 uM 24 h 0.19 0.79 0.0 0.0 0.0 0.0
91693 BRD-K66847579 MDAMB231 10 uM 24 h 0.0 0.0 0.0 0.46 1.63 2.41
91776 BRD-K66847579 SKBR3 0.08 uM 6 h 0.0 0.0 0.0 -0.2 -0.66 0.01
92866 BRD-K66847579 A375 10 uM 24 h 0.0 0.0 0.0 0.36 1.27 1.34
92894 BRD-K66847579 A549 0.04 uM 24 h 0.0 0.0 0.0 -0.41 -1.38 2.02
92930 BRD-K66847579 ASC 0.12 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
92993 BRD-K66847579 CD34 10 uM 24 h 0.0 0.0 0.0 -0.3 -1.01 0.56
93039 BRD-K66847579 HA1E 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
93081 BRD-K66847579 HEK293 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
93124 BRD-K66847579 HELA 10 uM 24 h 0.0 0.0 0.0 0.39 1.37 2.0
93169 BRD-K66847579 HEPG2 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
93219 BRD-K66847579 HUVEC 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
93274 BRD-K66847579 JURKAT 10 uM 24 h 0.25 1.03 0.13 -0.38 -1.28 1.45
93417 BRD-K66847579 NPC 0.12 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
93444 BRD-K66847579 PC3 10 uM 24 h 0.0 0.0 0.0 -0.26 -0.88 0.26
93510 BRD-K66847579 SKL 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
93541 BRD-K66847579 THP1 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
93581 BRD-K66847579 YAPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).