CMap Candidate Details

Structure:
CMap ID: C02366
Pert ID: BRD-A98299281
Compound Name: velnacrine
Targets: --
MoA: --
SMILES: Nc1c2C(O)CCCc2nc2ccccc12
InchiKey: HLVVITIHAZBPKB-UHFFFAOYSA-N
Compound Aliases: hydroxytacrine-maleate-(r,s)

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
6715 BRD-A98299281 A375 10 uM 24 h 0.19 0.79 0.0 -0.23 -0.77 0.09
6970 BRD-A98299281 A549 10 uM 24 h 0.0 0.0 0.0 0.26 0.93 0.27
7284 BRD-A98299281 HA1E 10 uM 24 h 0.0 0.0 0.0 0.28 1.0 0.42
7613 BRD-A98299281 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
7826 BRD-A98299281 HT29 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
8265 BRD-A98299281 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 -0.27 -0.91 0.31
8792 BRD-A98299281 VCAP 10 uM 6 h -0.23 -0.97 0.11 -0.3 -1.01 0.57
51910 BRD-A98299281 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
91000 BRD-A98299281 HUH7 15 uM 72 h 0.18 0.75 0.0 0.22 0.78 0.07
98124 BRD-A98299281 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
98323 BRD-A98299281 NEU 10 uM 24 h 0.25 1.05 0.17 -0.27 -0.91 0.3
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).