CMap Candidate Details

Structure:
CMap ID: C23695
Pert ID: BRD-K66944906
Compound Name: fraxidin
Targets: CA12
MoA: Carbonic anhydrase inhibitor
SMILES: COc1cc2ccc(=O)oc2c(OC)c1OC
InchiKey: RAYQKHLZHPFYEJ-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1605 BRD-K66944906 HA1E 10 uM 24 h 0.27 1.14 0.31 0.0 0.0 0.0
1945 BRD-K66944906 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
2410 BRD-K66944906 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
2577 BRD-K66944906 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41825 BRD-K66944906 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
41970 BRD-K66944906 A549 10 uM 24 h 0.0 0.0 0.0 -0.28 -0.95 0.42
42439 BRD-K66944906 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
42754 BRD-K66944906 HEPG2 10 uM 6 h 0.0 0.0 0.0 -0.31 -1.04 0.66
43053 BRD-K66944906 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43223 BRD-K66944906 MCF??7.00 10 uM 24 h 0.18 0.77 0.0 -0.31 -1.04 0.67
43619 BRD-K66944906 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
43920 BRD-K66944906 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
44175 BRD-K66944906 SKB 10 uM 24 h -0.21 -0.88 0.03 -0.26 -0.87 0.23
99357 BRD-K66944906 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).