CMap Candidate Details

Structure:
CMap ID: C23700
Pert ID: BRD-K66956375
Compound Name: oleoylethanolamide
Targets: GPR119; PPARA
MoA: PPAR receptor agonist; Potassium channel blocker; Cannabinoid receptor agonist; Glucose dependent insulinotropic receptor agonist
SMILES: CCCCCCCCC=C/CCCCCCCC(=O)NCCO
InchiKey: BOWVQLFMWHZBEF-KTKRTIGZSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
33643 BRD-K66956375 A375 10 uM 6 h 0.0 0.0 0.0 0.27 0.96 0.34
33826 BRD-K66956375 A549 10 uM 24 h 0.0 0.0 0.0 -0.25 -0.86 0.2
34153 BRD-K66956375 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
34400 BRD-K66956375 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
34663 BRD-K66956375 HCC515 10 uM 6 h 0.0 0.0 0.0 -0.45 -1.51 15.35
34932 BRD-K66956375 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
35180 BRD-K66956375 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
35435 BRD-K66956375 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 -0.42 -1.41 2.02
35982 BRD-K66956375 PC3 10 uM 24 h 0.2 0.85 0.01 0.0 0.0 0.0
36316 BRD-K66956375 PHH 10 uM 24 h -0.28 -1.15 0.43 -0.3 -1.02 0.61
36614 BRD-K66956375 SKB 10 uM 24 h 0.23 0.95 0.07 0.0 0.0 0.0
36852 BRD-K66956375 VCAP 10 uM 24 h 0.16 0.69 0.0 0.0 0.0 0.0
98924 BRD-K66956375 NEU 10 uM 24 h 0.0 0.0 0.0 -0.28 -0.94 0.39
99174 BRD-K66956375 NPC 10 uM 24 h -0.25 -1.04 0.21 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).