CMap Candidate Details

Structure:
CMap ID: C23757
Pert ID: BRD-K67121414
Compound Name: apixaban
Targets: F10
MoA: Coagulation factor inhibitor
SMILES: COc1ccc(cc1)-n1nc(C(N)=O)c2CCN(C(=O)c12)c1ccc(cc1)N1CCCCC1=O
InchiKey: QNZCBYKSOIHPEH-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
124987 BRD-K67121414 A549 0.125 uM 24 h 0.0 0.0 0.0 -0.36 -1.2 1.22
125064 BRD-K67121414 HT29 0.37 uM 24 h 0.0 0.0 0.0 0.25 0.89 0.2
125190 BRD-K67121414 THP1 0.04 uM 24 h 0.0 0.0 0.0 0.33 1.18 0.97
125225 BRD-K67121414 YAPC 0.125 uM 24 h 0.25 1.06 0.19 -0.29 -0.96 0.43
132990 BRD-K67121414 A375 0.08 uM 24 h 0.27 1.11 0.25 0.0 0.0 0.0
133026 BRD-K67121414 HA1E 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133106 BRD-K67121414 HELA 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133186 BRD-K67121414 JURKAT 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133211 BRD-K67121414 MCF10A 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133248 BRD-K67121414 MCF??7.00 0.08 uM 24 h 0.25 1.05 0.17 -0.32 -1.07 0.75
133276 BRD-K67121414 MDAMB231 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133306 BRD-K67121414 PC3 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).