CMap Candidate Details
Structure:
| CMap ID: | C23768 |
| Pert ID: | BRD-K67174588 |
| Compound Name: | toremifene |
| Targets: | ESR1 |
| MoA: | Estrogen receptor antagonist; Selective estrogen receptor modulator |
| SMILES: | CN(C)CCOc1ccc(cc1)C(=C(/CCCl)c1ccccc1)c1ccccc1 |
| InchiKey: | XFCLJVABOIYOMF-OCEACIFDSA-N |
| Compound Aliases: | -- |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 119411 | BRD-K67174588 | A375 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 119443 | BRD-K67174588 | A549 | 10 uM | 24 h | 0.21 | 0.87 | 0.01 | 0.0 | 0.0 | 0.0 |
| 119472 | BRD-K67174588 | HA1E | 10 uM | 24 h | 0.18 | 0.75 | 0.0 | 0.0 | 0.0 | 0.0 |
| 119510 | BRD-K67174588 | HCC515 | 3.33 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 119547 | BRD-K67174588 | HEPG2 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 119579 | BRD-K67174588 | HT29 | 10 uM | 24 h | -0.23 | -0.94 | 0.08 | 0.0 | 0.0 | 0.0 |
| 119607 | BRD-K67174588 | MCF??7.00 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 119640 | BRD-K67174588 | PC3 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |