CMap Candidate Details

Structure:
CMap ID: C02385
Pert ID: BRD-A99177642
Compound Name: deltaline
Targets: CHRNA7
MoA: Acetylcholine receptor antagonist
SMILES: CCN1C[C@]2(C)CC[C@H](OC)[C@@]34[C@@H]2[C@H](OC(=O)C)[C@@]5(OCO[C@]65C[C@H](OC)[C@H]7C[C@]4(O)[C@@H]6[C@H]7OC)C13
InchiKey: DTTPWCNKTMQMTE-DCRKHLHRSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1719 BRD-A99177642 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
2066 BRD-A99177642 HCC515 10 uM 6 h 0.19 0.8 0.0 0.0 0.0 0.0
2246 BRD-A99177642 PC3 10 uM 24 h -0.22 -0.91 0.05 -0.36 -1.2 1.18
2572 BRD-A99177642 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41697 BRD-A99177642 A375 10 uM 6 h -0.19 -0.79 0.0 -0.28 -0.93 0.34
42040 BRD-A99177642 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
42255 BRD-A99177642 ASC 10 uM 24 h 0.28 1.15 0.34 0.0 0.0 0.0
42591 BRD-A99177642 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
42897 BRD-A99177642 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43142 BRD-A99177642 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
43452 BRD-A99177642 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
43758 BRD-A99177642 PHH 10 uM 24 h 0.0 0.0 0.0 0.35 1.24 1.26
44042 BRD-A99177642 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
99939 BRD-A99177642 U2OS 4 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).