CMap Candidate Details

Structure:
CMap ID: C23853
Pert ID: BRD-K67439147
Compound Name: SIB-1893
Targets: GRM5
MoA: Glutamate receptor antagonist
SMILES: Cc1cccc(C=Cc2ccccc2)n1
InchiKey: SISOFUCTXZKSOQ-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5227 BRD-K67439147 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
5355 BRD-K67439147 HA1E 10 uM 24 h 0.19 0.8 0.0 0.0 0.0 0.0
5670 BRD-K67439147 HCC515 10 uM 24 h -0.16 -0.67 0.0 -0.24 -0.8 0.12
6213 BRD-K67439147 PC3 10 uM 24 h 0.26 1.08 0.21 0.0 0.0 0.0
6380 BRD-K67439147 VCAP 10 uM 24 h 0.0 0.0 0.0 -0.26 -0.87 0.23
44606 BRD-K67439147 A549 10 uM 24 h 0.0 0.0 0.0 -0.26 -0.87 0.24
45006 BRD-K67439147 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
45297 BRD-K67439147 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45560 BRD-K67439147 HT29 10 uM 6 h 0.21 0.86 0.01 -0.33 -1.12 0.93
45841 BRD-K67439147 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
46119 BRD-K67439147 NPC 10 uM 24 h 0.0 0.0 0.0 -0.33 -1.12 0.95
46434 BRD-K67439147 PHH 10 uM 24 h 0.27 1.11 0.26 0.0 0.0 0.0
46759 BRD-K67439147 SKB 10 uM 24 h 0.0 0.0 0.0 0.36 1.26 1.29
53528 BRD-K67439147 HUH7 2.5 uM 24 h 0.0 0.0 0.0 -0.23 -0.78 0.1
99367 BRD-K67439147 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).