CMap Candidate Details

Structure:
CMap ID: C23877
Pert ID: BRD-K67511046
Compound Name: naloxone
Targets: OPRD1; OPRK1; OPRM1
MoA: Opioid receptor antagonist
SMILES: Oc1ccc2C[C@H]3N(CC=C)CC[C@@]45[C@@H](Oc1c24)C(=O)CC[C@@]35O
InchiKey: UZHSEJADLWPNLE-GRGSLBFTSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
6796 BRD-K67511046 A375 10 uM 24 h 0.0 0.0 0.0 0.22 0.8 0.08
7191 BRD-K67511046 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
8022 BRD-K67511046 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
8259 BRD-K67511046 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
8404 BRD-K67511046 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
50222 BRD-K67511046 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
51053 BRD-K67511046 VCAP 10 uM 24 h 0.26 1.07 0.2 -0.34 -1.13 0.98
91302 BRD-K67511046 HUH7 10 uM 72 h -0.26 -1.1 0.34 -0.27 -0.92 0.33
99369 BRD-K67511046 U2OS 6.66 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).