CMap Candidate Details

Structure:
CMap ID: C00239
Pert ID: BRD-A09349126
Compound Name: norethindrone
Targets: PGR
MoA: Progestogen hormone; Progesterone receptor agonist
SMILES: CC(=O)O[C@]1(CCC2C3CCC4=CC(=O)CC[C@@H]4C3CC[C@@]21C)C#C
InchiKey: IMONTRJLAWHYGT-FJMAIUEKSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
6616 BRD-A09349126 A375 10 uM 24 h 0.27 1.12 0.27 0.0 0.0 0.0
7376 BRD-A09349126 HA1E 10 uM 6 h 0.0 0.0 0.0 -0.3 -1.0 0.55
8543 BRD-A09349126 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121186 BRD-A09349126 A549 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121315 BRD-A09349126 PC3 3.33 uM 24 h 0.3 1.24 0.53 0.0 0.0 0.0
129261 BRD-A09349126 HELA 2.22 uM 24 h 0.0 0.0 0.0 -0.4 -1.33 1.84
129297 BRD-A09349126 HT29 0.74 uM 24 h 0.0 0.0 0.0 0.23 0.83 0.11
129332 BRD-A09349126 MCF??7.00 0.25 uM 24 h 0.25 1.05 0.17 0.27 0.97 0.35
129372 BRD-A09349126 YAPC 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).