CMap Candidate Details

Structure:
CMap ID: C23902
Pert ID: BRD-K67566344
Compound Name: KU-0063794
Targets: MTOR
MoA: MTOR inhibitor
SMILES: COc1ccc(cc1CO)-c1ccc2c(nc(nc2n1)N1C[C@H](C)O[C@H](C)C1)N1CCOCC1
InchiKey: RFSMUFRPPYDYRD-CALCHBBNSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1224 BRD-K67566344 A549 1.11 uM 24 h -0.22 -0.93 0.07 -0.26 -0.89 0.26
1385 BRD-K67566344 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
8969 BRD-K67566344 A375 10 uM 24 h 0.0 0.0 0.0 -0.25 -0.85 0.2
9478 BRD-K67566344 AGS 10 uM 6 h -0.34 -1.4 1.14 0.0 0.0 0.0
9783 BRD-K67566344 H1299 10 uM 6 h -0.27 -1.11 0.37 -0.28 -0.95 0.39
10071 BRD-K67566344 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10156 BRD-K67566344 HCC515 10 uM 24 h 0.21 0.89 0.02 0.0 0.0 0.0
10565 BRD-K67566344 HCT116 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10824 BRD-K67566344 HEPG2 10 uM 6 h 0.0 0.0 0.0 -0.33 -1.09 0.85
10999 BRD-K67566344 HT29 10 uM 24 h 0.0 0.0 0.0 -0.27 -0.91 0.3
11167 BRD-K67566344 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 -0.25 -0.85 0.19
11543 BRD-K67566344 NCIH2073 10 uM 6 h 0.0 0.0 0.0 -0.32 -1.07 0.78
11810 BRD-K67566344 NCIH508 10 uM 6 h 0.0 0.0 0.0 -0.42 -1.41 2.02
12102 BRD-K67566344 NCIH596 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12362 BRD-K67566344 NOMO1 10 uM 6 h 0.0 0.0 0.0 -0.33 -1.13 0.97
12481 BRD-K67566344 PC3 10 uM 24 h 0.0 0.0 0.0 -0.29 -0.96 0.43
12997 BRD-K67566344 THP1 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
13328 BRD-K67566344 U937 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
13657 BRD-K67566344 VCAP 10 uM 6 h 0.0 0.0 0.0 -0.27 -0.91 0.31
95996 BRD-K67566344 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).