CMap Candidate Details
Structure:
| CMap ID: | C02391 |
| Pert ID: | BRD-A99367815 |
| Compound Name: | fumagillin |
| Targets: | METAP2 |
| MoA: | Methionine aminopeptidase inhibitor |
| SMILES: | CO[C@@H]1[C@@H](CC[C@]2(CO2)C1[C@@]1(C)O[C@@H]1CC=C(C)C)OC(=O)C=CC=CC=CC=CC(O)=O |
| InchiKey: | NGGMYCMLYOUNGM-ZVVCMXCESA-N |
| Compound Aliases: | -- |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 90963 | BRD-A99367815 | HUH7 | 6.66 uM | 72 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 96495 | BRD-A99367815 | A375 | 3.33 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 96562 | BRD-A99367815 | PC3 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.28 | 1.0 | 0.42 |