CMap Candidate Details

Structure:
CMap ID: C23924
Pert ID: BRD-K67637637
Compound Name: olopatadine
Targets: HRH1
MoA: Histamine receptor antagonist
SMILES: CN(C)CC/C=C1/c2ccccc2COc3ccc(CC(=O)O)cc13
InchiKey: JBIMVDZLSHOPLA-LSCVHKIXSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
22036 BRD-K67637637 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
22323 BRD-K67637637 A549 10 uM 6 h -0.3 -1.24 0.67 0.2 0.72 0.02
22543 BRD-K67637637 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
22824 BRD-K67637637 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
23121 BRD-K67637637 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
23414 BRD-K67637637 HT29 10 uM 6 h -0.27 -1.12 0.38 -0.36 -1.2 1.19
23618 BRD-K67637637 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
24023 BRD-K67637637 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
24194 BRD-K67637637 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
91090 BRD-K67637637 HUH7 10 uM 72 h -0.32 -1.32 0.83 -0.27 -0.91 0.3
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).