CMap Candidate Details

Structure:
CMap ID: C23969
Pert ID: BRD-K67783091
Compound Name: haloperidol
Targets: DRD1; DRD2; DRD3; DRD4; HTR2A
MoA: Dopamine receptor antagonist
SMILES: OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1
InchiKey: LNEPOXFFQSENCJ-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1443 BRD-K67783091 NPC 25 uM 24 h 0.0 0.0 0.0 0.33 1.16 0.9
7709 BRD-K67783091 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
23122 BRD-K67783091 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
24195 BRD-K67783091 VCAP 10 uM 24 h 0.21 0.86 0.01 0.0 0.0 0.0
91132 BRD-K67783091 HUH7 8 uM 72 h 0.0 0.0 0.0 0.0 0.0 0.0
99374 BRD-K67783091 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
124585 BRD-K67783091 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
124626 BRD-K67783091 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
124671 BRD-K67783091 HELA 0.04 uM 24 h 0.0 0.0 0.0 0.32 1.13 0.84
124706 BRD-K67783091 HT29 10 uM 24 h -0.29 -1.21 0.57 0.0 0.0 0.0
124733 BRD-K67783091 JURKAT 0.125 uM 24 h 0.24 0.98 0.09 0.0 0.0 0.0
124768 BRD-K67783091 MCF??7.00 10 uM 24 h 0.27 1.14 0.32 0.0 0.0 0.0
124811 BRD-K67783091 MDAMB231 10 uM 24 h -0.25 -1.02 0.19 0.0 0.0 0.0
124854 BRD-K67783091 PC3 10 uM 24 h -0.22 -0.91 0.05 0.0 0.0 0.0
124896 BRD-K67783091 THP1 1.11 uM 24 h -0.22 -0.91 0.05 -0.35 -1.19 1.16
124920 BRD-K67783091 YAPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132702 BRD-K67783091 A549 0.25 uM 24 h 0.22 0.93 0.05 0.0 0.0 0.0
132768 BRD-K67783091 HEK293 0.74 uM 24 h 0.0 0.0 0.0 -0.28 -0.95 0.39
132883 BRD-K67783091 MCF10A 0.01 uM 24 h 0.0 0.0 0.0 0.34 1.22 1.15
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).