CMap Candidate Details

Structure:
CMap ID: C23985
Pert ID: BRD-K67831364
Compound Name: ZM-323881
Targets: KDR
MoA: VEGFR inhibitor
SMILES: Cc1cc(F)c(Nc2ncnc3cc(OCc4ccccc4)ccc23)cc1O
InchiKey: NVBNDZZLJRYRPD-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
4134 BRD-K67831364 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
4589 BRD-K67831364 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
4707 BRD-K67831364 PC3 10 uM 24 h -0.23 -0.97 0.11 0.25 0.89 0.21
5111 BRD-K67831364 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39161 BRD-K67831364 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39475 BRD-K67831364 A549 10 uM 6 h 0.0 0.0 0.0 -0.23 -0.78 0.1
39745 BRD-K67831364 ASC 10 uM 24 h -0.29 -1.22 0.61 -0.36 -1.22 1.24
40039 BRD-K67831364 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40307 BRD-K67831364 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40631 BRD-K67831364 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 -0.18 -0.62 0.0
41162 BRD-K67831364 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41500 BRD-K67831364 SKB 10 uM 24 h 0.0 0.0 0.0 -0.36 -1.22 1.24
99375 BRD-K67831364 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).