CMap Candidate Details

Structure:
CMap ID: C24002
Pert ID: BRD-K67868012
Compound Name: PI-103
Targets: MTOR; PIK3CA; PIK3CB; PIK3CD; PIK3CG
MoA: MTOR inhibitor; PI3K inhibitor
SMILES: Oc1cccc(c1)-c1nc(N2CCOCC2)c2oc3ncccc3c2n1
InchiKey: TUVCWJQQGGETHL-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1246 BRD-K67868012 A549 1.11 uM 48 h 0.0 0.0 0.0 0.0 0.0 0.0
1389 BRD-K67868012 U2OS 1.11 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
9480 BRD-K67868012 AGS 12 uM 6 h 0.0 0.0 0.0 0.23 0.81 0.09
9785 BRD-K67868012 H1299 12 uM 6 h -0.26 -1.1 0.34 -0.25 -0.84 0.18
10567 BRD-K67868012 HCT116 12 uM 6 h -0.3 -1.26 0.71 0.26 0.92 0.25
10827 BRD-K67868012 HEPG2 12 uM 6 h -0.23 -0.97 0.11 0.32 1.13 0.8
11546 BRD-K67868012 NCIH2073 12 uM 6 h 0.0 0.0 0.0 0.32 1.14 0.87
11812 BRD-K67868012 NCIH508 12 uM 6 h -0.25 -1.06 0.26 0.0 0.0 0.0
12104 BRD-K67868012 NCIH596 12 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12363 BRD-K67868012 NOMO1 12 uM 6 h 0.0 0.0 0.0 -0.19 -0.62 0.0
13018 BRD-K67868012 THP1 12 uM 6 h 0.24 1.0 0.11 0.0 0.0 0.0
13331 BRD-K67868012 U937 12 uM 6 h 0.0 0.0 0.0 0.29 1.04 0.56
13660 BRD-K67868012 VCAP 12 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
91849 BRD-K67868012 MCF10A 2.22 uM 24 h 0.2 0.81 0.0 -0.21 -0.71 0.03
91900 BRD-K67868012 MDAMB231 10 uM 24 h 0.0 0.0 0.0 -0.39 -1.3 1.57
91945 BRD-K67868012 SKBR3 10 uM 24 h 0.0 0.0 0.0 -0.34 -1.13 0.99
92469 BRD-K67868012 BT20 10 uM 24 h 0.0 0.0 0.0 -0.28 -0.96 0.43
92537 BRD-K67868012 HME1 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
92608 BRD-K67868012 HS578T 10 uM 3 h 0.0 0.0 0.0 0.33 1.15 0.89
92631 BRD-K67868012 HT29 3.33 uM 24 h 0.0 0.0 0.0 -0.25 -0.83 0.16
92672 BRD-K67868012 LNCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
95984 BRD-K67868012 PHH 10 uM 24 h 0.0 0.0 0.0 0.24 0.84 0.13
98925 BRD-K67868012 NEU 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
99247 BRD-K67868012 NPC 10 uM 6 h 0.0 0.0 0.0 0.24 0.85 0.14
117350 BRD-K67868012 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
117428 BRD-K67868012 HA1E 10 uM 24 h 0.0 0.0 0.0 -0.25 -0.85 0.19
117473 BRD-K67868012 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121691 BRD-K67868012 MCF??7.00 10 uM 24 h 0.22 0.93 0.04 0.0 0.0 0.0
129615 BRD-K67868012 HELA 2.22 uM 24 h 0.0 0.0 0.0 -0.25 -0.85 0.19
129708 BRD-K67868012 PC3 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129741 BRD-K67868012 YAPC 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).