CMap Candidate Details

Structure:
CMap ID: C24031
Pert ID: BRD-K67977190
Compound Name: eprosartan
Targets: AGTR1
MoA: Angiotensin receptor antagonist
SMILES: CCCCc1ncc(C=C(/Cc2cccs2)C(O)=O)n1Cc1ccc(cc1)C(O)=O
InchiKey: OROAFUQRIXKEMV-LDADJPATSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
50040 BRD-K67977190 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
50223 BRD-K67977190 HA1E 10 uM 6 h 0.0 0.0 0.0 0.29 1.02 0.46
50571 BRD-K67977190 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
50775 BRD-K67977190 MCF??7.00 10 uM 6 h 0.21 0.88 0.02 0.24 0.84 0.13
51054 BRD-K67977190 VCAP 10 uM 24 h 0.21 0.87 0.01 0.23 0.81 0.09
91166 BRD-K67977190 HUH7 8 uM 72 h 0.0 0.0 0.0 -0.3 -1.0 0.52
97173 BRD-K67977190 A375 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
97235 BRD-K67977190 PC3 3.33 uM 24 h 0.19 0.77 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).