CMap Candidate Details

Structure:
CMap ID: C24071
Pert ID: BRD-K68103045
Compound Name: CGS-20625
Targets: GABRA1; GABRA2; GABRA3; GABRA4; GABRA5; GABRA6
MoA: Benzodiazepine receptor agonist
SMILES: COc1ccc(cc1)-n1nc2c3CCCCCc3[nH]cc2c1=O
InchiKey: XRUUVUYJUULCBQ-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
4467 BRD-K68103045 HCC515 10 uM 24 h 0.0 0.0 0.0 0.32 1.15 0.88
5113 BRD-K68103045 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39746 BRD-K68103045 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
40851 BRD-K68103045 NEU 10 uM 24 h -0.26 -1.1 0.34 0.0 0.0 0.0
41163 BRD-K68103045 NPC 10 uM 24 h 0.29 1.2 0.42 0.0 0.0 0.0
41501 BRD-K68103045 SKB 10 uM 24 h 0.24 1.0 0.11 0.0 0.0 0.0
126416 BRD-K68103045 HEK293 10 uM 24 h -0.24 -0.99 0.14 0.27 0.94 0.29
126465 BRD-K68103045 HELA 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
126488 BRD-K68103045 HT29 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
126507 BRD-K68103045 MCF10A 0.37 uM 24 h -0.34 -1.42 1.43 -0.25 -0.85 0.2
126530 BRD-K68103045 MCF??7.00 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
126589 BRD-K68103045 YAPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134337 BRD-K68103045 A375 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134367 BRD-K68103045 A549 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134388 BRD-K68103045 HA1E 0.03 uM 24 h 0.0 0.0 0.0 -0.35 -1.18 1.15
134483 BRD-K68103045 HUVEC 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134584 BRD-K68103045 MDAMB231 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134616 BRD-K68103045 PC3 0.08 uM 24 h 0.0 0.0 0.0 0.35 1.23 1.19
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).