CMap Candidate Details

Structure:
CMap ID: C24099
Pert ID: BRD-K68190965
Compound Name: GR-46611
Targets: HTR1D
MoA: Serotonin receptor agonist
SMILES: COc1ccc(CNC(=O)C=Cc2ccc3[nH]cc(CCN(C)C)c3c2)cc1
InchiKey: LBVZWEWTNUDWNS-YRNVUSSQSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
4237 BRD-K68190965 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
4468 BRD-K68190965 HCC515 10 uM 24 h 0.21 0.88 0.02 0.0 0.0 0.0
4708 BRD-K68190965 PC3 10 uM 24 h 0.0 0.0 0.0 0.35 1.26 1.29
4952 BRD-K68190965 VCAP 10 uM 24 h 0.0 0.0 0.0 -0.31 -1.05 0.69
39162 BRD-K68190965 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39476 BRD-K68190965 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39747 BRD-K68190965 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
40040 BRD-K68190965 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.24 0.86 0.16
40308 BRD-K68190965 HT29 10 uM 6 h 0.0 0.0 0.0 0.31 1.09 0.67
40495 BRD-K68190965 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
40852 BRD-K68190965 NEU 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41164 BRD-K68190965 NPC 10 uM 24 h 0.0 0.0 0.0 -0.23 -0.78 0.1
41502 BRD-K68190965 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
99380 BRD-K68190965 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).