CMap Candidate Details

Structure:
CMap ID: C24101
Pert ID: BRD-K68191783
Compound Name: ALW-II-38-3
Targets: DDR1
MoA: Ephrin inhibitor
SMILES: Cc1cn(cn1)-c1cc(cc(c1)C(F)(F)F)C(=O)Nc1ccc(C)c(NC(=O)c2ccno2)c1
InchiKey: IYUFHBXMTTXZBE-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
29922 BRD-K68191783 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
30232 BRD-K68191783 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
30817 BRD-K68191783 HA1E 10 uM 6 h 0.0 0.0 0.0 -0.25 -0.84 0.17
31421 BRD-K68191783 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
31657 BRD-K68191783 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
32815 BRD-K68191783 PC3 10 uM 6 h -0.19 -0.8 0.0 0.0 0.0 0.0
33108 BRD-K68191783 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
33341 BRD-K68191783 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
91520 BRD-K68191783 BT20 10 uM 24 h 0.0 0.0 0.0 -0.39 -1.31 1.71
91609 BRD-K68191783 HS578T 10 uM 6 h 0.0 0.0 0.0 -0.32 -1.09 0.82
91694 BRD-K68191783 MDAMB231 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
91724 BRD-K68191783 SKBR3 10 uM 24 h 0.0 0.0 0.0 0.33 1.17 0.94
94520 BRD-K68191783 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
94569 BRD-K68191783 CD34 10 uM 24 h 0.0 0.0 0.0 0.22 0.78 0.07
94613 BRD-K68191783 HCC515 10 uM 24 h -0.23 -0.95 0.09 -0.24 -0.82 0.14
94657 BRD-K68191783 HEK293 10 uM 24 h -0.3 -1.25 0.68 -0.28 -0.94 0.38
94706 BRD-K68191783 HELA 0.12 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
94764 BRD-K68191783 HME1 10 uM 24 h 0.28 1.18 0.39 0.0 0.0 0.0
94856 BRD-K68191783 HUVEC 10 uM 24 h 0.22 0.93 0.04 -0.4 -1.36 2.02
94906 BRD-K68191783 JURKAT 10 uM 24 h -0.36 -1.49 1.43 -0.3 -1.01 0.55
94952 BRD-K68191783 MCF10A 10 uM 24 h 0.0 0.0 0.0 -0.29 -0.99 0.5
94987 BRD-K68191783 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
95034 BRD-K68191783 NEU 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
95095 BRD-K68191783 NPC 10 uM 24 h -0.23 -0.94 0.08 -0.28 -0.96 0.42
95182 BRD-K68191783 SHSY5Y 10 uM 24 h 0.0 0.0 0.0 -0.25 -0.85 0.2
95243 BRD-K68191783 SKL 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
95291 BRD-K68191783 THP1 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).