CMap Candidate Details

Structure:
CMap ID: C24114
Pert ID: BRD-K68232413
Compound Name: etizolam
Targets: GABRA1
MoA: Benzodiazepine receptor agonist
SMILES: CCc1cc2c(s1)-n1c(C)nnc1CN=C2c1ccccc1Cl
InchiKey: VMZUTJCNQWMAGF-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
97126 BRD-K68232413 A375 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
126370 BRD-K68232413 A549 10 uM 24 h 0.21 0.86 0.01 0.0 0.0 0.0
126420 BRD-K68232413 HEK293 10 uM 24 h 0.23 0.94 0.06 0.0 0.0 0.0
126512 BRD-K68232413 MCF10A 1.11 uM 24 h 0.0 0.0 0.0 0.25 0.87 0.17
126548 BRD-K68232413 MDAMB231 10 uM 24 h 0.21 0.88 0.01 0.33 1.15 0.9
126592 BRD-K68232413 YAPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134390 BRD-K68232413 HA1E 0.01 uM 24 h -0.25 -1.04 0.21 0.25 0.9 0.21
134420 BRD-K68232413 HELA 2.22 uM 24 h 0.0 0.0 0.0 0.32 1.13 0.82
134450 BRD-K68232413 HT29 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134487 BRD-K68232413 HUVEC 0.74 uM 24 h 0.0 0.0 0.0 0.28 0.99 0.39
134560 BRD-K68232413 MCF??7.00 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134617 BRD-K68232413 PC3 0.25 uM 24 h 0.25 1.05 0.17 0.34 1.21 1.15
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).