CMap Candidate Details

Structure:
CMap ID: C24126
Pert ID: BRD-K68264559
Compound Name: brimonidine
Targets: ADRA2A; ADRA2B; ADRA2C
MoA: Adrenergic receptor agonist
SMILES: Brc1c(NC2=NCCN2)ccc2nccnc12
InchiKey: XYLJNLCSTIOKRM-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
2917 BRD-K68264559 HA1E 10 uM 24 h 0.0 0.0 0.0 -0.34 -1.16 1.11
3251 BRD-K68264559 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
39163 BRD-K68264559 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39341 BRD-K68264559 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
39748 BRD-K68264559 ASC 10 uM 24 h 0.0 0.0 0.0 -0.34 -1.14 1.02
40041 BRD-K68264559 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40309 BRD-K68264559 HT29 10 uM 6 h 0.0 0.0 0.0 -0.37 -1.23 1.28
40496 BRD-K68264559 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41165 BRD-K68264559 NPC 10 uM 24 h 0.0 0.0 0.0 -0.34 -1.13 1.0
41503 BRD-K68264559 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
50943 BRD-K68264559 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
51055 BRD-K68264559 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
99382 BRD-K68264559 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).