CMap Candidate Details

Structure:
CMap ID: C24174
Pert ID: BRD-K68392338
Compound Name: ZK-93426
Targets: GABRA1
MoA: Benzodiazepine receptor antagonist
SMILES: CCOC(=O)c1ncc2[nH]c3cccc(OC(C)C)c3c2c1C
InchiKey: VMDUABMKBUKKPG-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1954 BRD-K68392338 HCC515 10 uM 24 h 0.24 1.0 0.1 0.0 0.0 0.0
2581 BRD-K68392338 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
42449 BRD-K68392338 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
42762 BRD-K68392338 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43627 BRD-K68392338 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
44184 BRD-K68392338 SKB 10 uM 24 h -0.22 -0.91 0.05 0.0 0.0 0.0
99386 BRD-K68392338 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
126620 BRD-K68392338 A375 10 uM 24 h -0.22 -0.93 0.07 0.0 0.0 0.0
126645 BRD-K68392338 A549 10 uM 24 h 0.0 0.0 0.0 -0.3 -1.02 0.61
126665 BRD-K68392338 HA1E 10 uM 24 h 0.0 0.0 0.0 -0.3 -1.0 0.53
126707 BRD-K68392338 HELA 10 uM 24 h 0.0 0.0 0.0 -0.29 -0.99 0.51
126735 BRD-K68392338 HT29 10 uM 24 h 0.0 0.0 0.0 -0.31 -1.05 0.71
126795 BRD-K68392338 MCF10A 10 uM 24 h 0.0 0.0 0.0 -0.32 -1.09 0.84
126828 BRD-K68392338 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
126870 BRD-K68392338 MDAMB231 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
126908 BRD-K68392338 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
126931 BRD-K68392338 THP1 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
126981 BRD-K68392338 YAPC 10 uM 24 h -0.26 -1.07 0.27 -0.2 -0.66 0.01
134753 BRD-K68392338 HEK293 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134846 BRD-K68392338 HUVEC 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134897 BRD-K68392338 JURKAT 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).