CMap Candidate Details

Structure:
CMap ID: C00242
Pert ID: BRD-A09467419
Compound Name: mebeverine
Targets: CHRM1
MoA: Acetylcholine receptor antagonist
SMILES: CCN(CCCCOC(=O)c1ccc(OC)c(OC)c1)C(C)Cc1ccc(OC)cc1
InchiKey: VYVKHNNGDFVQGA-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5144 BRD-A09467419 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
5251 BRD-A09467419 HA1E 10 uM 24 h 0.0 0.0 0.0 0.27 0.97 0.35
5493 BRD-A09467419 HCC515 10 uM 24 h 0.0 0.0 0.0 0.34 1.2 1.13
5822 BRD-A09467419 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
6233 BRD-A09467419 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
6344 BRD-A09467419 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
39260 BRD-A09467419 A549 10 uM 24 h 0.21 0.88 0.02 0.2 0.72 0.02
39546 BRD-A09467419 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
40162 BRD-A09467419 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40557 BRD-A09467419 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40679 BRD-A09467419 NEU 10 uM 24 h 0.0 0.0 0.0 -0.31 -1.06 0.73
40972 BRD-A09467419 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41296 BRD-A09467419 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).