CMap Candidate Details

Structure:
CMap ID: C24289
Pert ID: BRD-K68747584
Compound Name: PF-03814735
Targets: --
MoA: --
SMILES: CC(=O)NCC(=O)N1[C@H]2CC[C@@H]1c1cc(Nc3ncc(c(NC4CCC4)n3)C(F)(F)F)ccc21
InchiKey: RYYNGWLOYLRZLK-RBUKOAKNSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
126356 BRD-K68747584 A375 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
126373 BRD-K68747584 A549 3.33 uM 24 h -0.3 -1.26 0.72 0.0 0.0 0.0
126423 BRD-K68747584 HEK293 1.11 uM 24 h 0.28 1.18 0.39 -0.31 -1.05 0.69
126468 BRD-K68747584 HELA 1.11 uM 24 h 0.0 0.0 0.0 0.37 1.31 1.59
126514 BRD-K68747584 MCF10A 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
126549 BRD-K68747584 MDAMB231 10 uM 24 h 0.0 0.0 0.0 0.3 1.05 0.57
126571 BRD-K68747584 PC3 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134391 BRD-K68747584 HA1E 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134453 BRD-K68747584 HT29 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134490 BRD-K68747584 HUVEC 2.22 uM 24 h 0.0 0.0 0.0 -0.39 -1.3 1.59
134562 BRD-K68747584 MCF??7.00 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134646 BRD-K68747584 YAPC 2.22 uM 24 h 0.0 0.0 0.0 0.3 1.06 0.61
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).