CMap Candidate Details

Structure:
CMap ID: C02432
Pert ID: BRD-K00088062
Compound Name: cyanoquinoline-11
Targets: --
MoA: --
SMILES: Fc1ccc(Nc2c(cnc3c(Cl)cc(NCc4cnc[nH]4)cc23)C#N)cc1Cl
InchiKey: ONXROKMQGCSOMG-UHFFFAOYSA-N
Compound Aliases: CYANOQUINOLINE-11

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
8891 BRD-K00088062 A375 40 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
9159 BRD-K00088062 A549 40 uM 6 h -0.22 -0.94 0.07 0.0 0.0 0.0
9324 BRD-K00088062 AGS 40 uM 6 h 0.0 0.0 0.0 0.3 1.06 0.6
9628 BRD-K00088062 H1299 40 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
9924 BRD-K00088062 HA1E 40 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
10302 BRD-K00088062 HCC515 40 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10428 BRD-K00088062 HCT116 40 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10701 BRD-K00088062 HEPG2 40 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10922 BRD-K00088062 HT29 40 uM 24 h -0.27 -1.12 0.38 -0.21 -0.7 0.03
11256 BRD-K00088062 MCF??7.00 40 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
11378 BRD-K00088062 NCIH2073 40 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
11682 BRD-K00088062 NCIH508 40 uM 6 h 0.22 0.93 0.05 0.0 0.0 0.0
11950 BRD-K00088062 NCIH596 40 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12233 BRD-K00088062 NOMO1 40 uM 6 h 0.0 0.0 0.0 0.31 1.11 0.71
13176 BRD-K00088062 U937 40 uM 6 h -0.23 -0.96 0.1 0.0 0.0 0.0
13557 BRD-K00088062 VCAP 40 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
96947 BRD-K00088062 PC3 10 uM 24 h 0.0 0.0 0.0 0.38 1.33 1.72
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).