CMap Candidate Details

Structure:
CMap ID: C24341
Pert ID: BRD-K68938568
Compound Name: GDC-0152
Targets: --
MoA: --
SMILES: CN[C@@H](C)C(=O)N[C@@H](C1CCCCC1)C(=O)N1CCC[C@H]1C(=O)Nc1snnc1-c1ccccc1
InchiKey: WZRFLSDVFPIXOV-LRQRDZAKSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
126365 BRD-K68938568 A375 0.37 uM 24 h 0.0 0.0 0.0 0.3 1.06 0.59
126406 BRD-K68938568 HA1E 10 uM 24 h -0.26 -1.1 0.35 -0.23 -0.78 0.09
126450 BRD-K68938568 HEK293 10 uM 24 h -0.18 -0.76 0.0 0.0 0.0 0.0
126528 BRD-K68938568 MCF10A 10 uM 24 h 0.0 0.0 0.0 -0.28 -0.95 0.4
126611 BRD-K68938568 YAPC 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134381 BRD-K68938568 A549 2.22 uM 24 h -0.32 -1.33 0.92 -0.4 -1.33 1.85
134437 BRD-K68938568 HELA 0.25 uM 24 h 0.0 0.0 0.0 -0.3 -0.99 0.51
134471 BRD-K68938568 HT29 2.22 uM 24 h 0.0 0.0 0.0 -0.36 -1.21 1.24
134517 BRD-K68938568 HUVEC 0.01 uM 24 h 0.29 1.2 0.44 0.0 0.0 0.0
134574 BRD-K68938568 MCF??7.00 0.08 uM 24 h -0.21 -0.86 0.02 0.0 0.0 0.0
134606 BRD-K68938568 MDAMB231 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134631 BRD-K68938568 PC3 2.22 uM 24 h 0.0 0.0 0.0 -0.41 -1.37 2.02
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).