CMap Candidate Details

Structure:
CMap ID: C24455
Pert ID: BRD-K69328504
Compound Name: L-690488
Targets: IMPA1
MoA: IMPase inhibitor
SMILES: CC(C)(C)C(=O)OCOP(=O)(OCOC(=O)C(C)(C)C)C(C)(Oc1ccc(O)cc1)P(=O)(OCOC(=O)C(C)(C)C)OCOC(=O)C(C)(C)C
InchiKey: LOTSPVPQHAUHCE-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
8972 BRD-K69328504 A375 10 uM 24 h 0.0 0.0 0.0 0.31 1.11 0.74
9113 BRD-K69328504 A549 10 uM 24 h -0.25 -1.04 0.22 0.17 0.59 0.0
9488 BRD-K69328504 AGS 10 uM 6 h 0.0 0.0 0.0 -0.23 -0.76 0.07
9793 BRD-K69328504 H1299 10 uM 6 h 0.0 0.0 0.0 -0.21 -0.72 0.04
9982 BRD-K69328504 HA1E 10 uM 24 h 0.0 0.0 0.0 -0.35 -1.17 1.14
10233 BRD-K69328504 HCC515 10 uM 24 h 0.0 0.0 0.0 -0.31 -1.05 0.7
10574 BRD-K69328504 HCT116 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10831 BRD-K69328504 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
11006 BRD-K69328504 HT29 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
11230 BRD-K69328504 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
11554 BRD-K69328504 NCIH2073 10 uM 6 h 0.0 0.0 0.0 -0.31 -1.04 0.68
11818 BRD-K69328504 NCIH508 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12370 BRD-K69328504 NOMO1 10 uM 6 h 0.17 0.73 0.0 -0.36 -1.22 1.25
12557 BRD-K69328504 PC3 10 uM 24 h 0.0 0.0 0.0 -0.3 -1.0 0.53
12850 BRD-K69328504 SW480 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
13090 BRD-K69328504 THP1 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
13338 BRD-K69328504 U937 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
13496 BRD-K69328504 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).