CMap Candidate Details

Structure:
CMap ID: C00246
Pert ID: BRD-A09539288
Compound Name: homatropine
Targets: CHRM1
MoA: Acetylcholine receptor antagonist
SMILES: CN1C2CC[C@H]1C[C@H](C2)OC(=O)C(O)c1ccccc1
InchiKey: ZTVIKZXZYLEVOL-FGZQJIAISA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
6617 BRD-A09539288 A375 10 uM 24 h -0.22 -0.93 0.07 0.0 0.0 0.0
6913 BRD-A09539288 A549 10 uM 24 h -0.24 -0.99 0.13 0.0 0.0 0.0
7203 BRD-A09539288 HA1E 10 uM 24 h 0.2 0.81 0.0 0.19 0.67 0.01
7503 BRD-A09539288 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
7935 BRD-A09539288 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
8126 BRD-A09539288 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
8425 BRD-A09539288 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
8544 BRD-A09539288 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).