CMap Candidate Details

Structure:
CMap ID: C24635
Pert ID: BRD-K69840642
Compound Name: ISOX
Targets: HDAC6
MoA: HDAC inhibitor
SMILES: CC(C)(C)OC(=O)Nc1ccc(cc1)-c1cc(no1)C(=O)NCCCCCCC(=O)NO
InchiKey: WWGBHDIHIVGYLZ-UHFFFAOYSA-N
Compound Aliases: isox

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
8974 BRD-K69840642 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
9224 BRD-K69840642 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
9490 BRD-K69840642 AGS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
9794 BRD-K69840642 H1299 10 uM 6 h -0.2 -0.84 0.01 0.0 0.0 0.0
9880 BRD-K69840642 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
10256 BRD-K69840642 HCC515 10 uM 6 h 0.17 0.73 0.0 0.3 1.05 0.58
10576 BRD-K69840642 HCT116 10 uM 6 h 0.0 0.0 0.0 0.3 1.07 0.63
10833 BRD-K69840642 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
11059 BRD-K69840642 HT29 10 uM 6 h 0.0 0.0 0.0 0.27 0.94 0.29
11138 BRD-K69840642 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 -0.23 -0.78 0.09
11555 BRD-K69840642 NCIH2073 10 uM 6 h -0.26 -1.09 0.33 0.28 1.01 0.43
11820 BRD-K69840642 NCIH508 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12112 BRD-K69840642 NCIH596 10 uM 6 h 0.0 0.0 0.0 -0.23 -0.77 0.09
12371 BRD-K69840642 NOMO1 10 uM 6 h 0.18 0.77 0.0 0.0 0.0 0.0
12438 BRD-K69840642 PC3 10 uM 24 h 0.0 0.0 0.0 -0.27 -0.92 0.32
12851 BRD-K69840642 SW480 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12939 BRD-K69840642 THP1 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
13340 BRD-K69840642 U937 10 uM 6 h 0.0 0.0 0.0 -0.21 -0.71 0.04
13497 BRD-K69840642 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
95978 BRD-K69840642 PHH 10 uM 24 h 0.0 0.0 0.0 -0.29 -0.99 0.51
99080 BRD-K69840642 NEU 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
99248 BRD-K69840642 NPC 10 uM 6 h -0.2 -0.83 0.0 -0.37 -1.26 1.35
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).