CMap Candidate Details

Structure:
CMap ID: C24647
Pert ID: BRD-K69888333
Compound Name: BRD-K69888333
Targets: --
MoA: --
SMILES: C[C@H](CO)N1C[C@H](C)[C@H](CN(C)Cc2ccc(cc2)C(=O)Nc3ccccc3N)Oc4c(NC(=O)c5ccc(cc5)c6nccs6)cccc4C1=O
InchiKey: UIWHTZIAIXNFGN-XUKQSAIQSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
25773 BRD-K69888333 A375 10 uM 6 h 0.22 0.93 0.05 0.0 0.0 0.0
25974 BRD-K69888333 A549 10 uM 24 h 0.0 0.0 0.0 -0.23 -0.79 0.11
26432 BRD-K69888333 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
26756 BRD-K69888333 HA1E 10 uM 6 h 0.0 0.0 0.0 -0.3 -1.02 0.59
27058 BRD-K69888333 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
27368 BRD-K69888333 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
27592 BRD-K69888333 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
28002 BRD-K69888333 NEU 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
28315 BRD-K69888333 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
28513 BRD-K69888333 PC3 10 uM 24 h 0.0 0.0 0.0 -0.43 -1.43 15.35
28949 BRD-K69888333 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
29283 BRD-K69888333 SKB 10 uM 24 h 0.23 0.97 0.08 -0.18 -0.6 0.0
29523 BRD-K69888333 VCAP 10 uM 24 h 0.0 0.0 0.0 -0.22 -0.76 0.07
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).