CMap Candidate Details

Structure:
CMap ID: C24736
Pert ID: BRD-K70241288
Compound Name: L-692585
Targets: GHSR
MoA: Growth hormone releasing peptide ligand agonist
SMILES: C[C@@H](O)CNC(C)(C)CC(=O)N[C@@H]1CCc2ccccc2N(Cc3ccc(cc3)c4ccccc4c5nn[nH]n5)C1=O
InchiKey: AYBCFPXLXOLPIZ-JIPXPUAJSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
4241 BRD-K70241288 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
4471 BRD-K70241288 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
4712 BRD-K70241288 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
5116 BRD-K70241288 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
44433 BRD-K70241288 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
44608 BRD-K70241288 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
45010 BRD-K70241288 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
45302 BRD-K70241288 HEPG2 10 uM 6 h 0.25 1.05 0.16 0.0 0.0 0.0
45564 BRD-K70241288 HT29 10 uM 6 h 0.0 0.0 0.0 -0.33 -1.11 0.9
45712 BRD-K70241288 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
46124 BRD-K70241288 NPC 10 uM 24 h -0.22 -0.93 0.07 0.0 0.0 0.0
46438 BRD-K70241288 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
46763 BRD-K70241288 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
99402 BRD-K70241288 U2OS 10 uM 6 h -0.24 -1.02 0.17 -0.24 -0.82 0.15
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).