CMap Candidate Details

Structure:
CMap ID: C00248
Pert ID: BRD-A09722536
Compound Name: cyclophosphamide
Targets: CYP2A6; CYP3A7; CYP2B6; CYP2C19; CYP2C8; CYP2C9; CYP2C18; CYP2D6; CYP3A4; CYP3A5
MoA: DNA alkylating agent
SMILES: ClCCN(CCCl)P1(=O)NCCCO1
InchiKey: CMSMOCZEIVJLDB-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
50799 BRD-A09722536 PC3 10 uM 24 h 0.0 0.0 0.0 0.35 1.25 1.28
50972 BRD-A09722536 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
52074 BRD-A09722536 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
52370 BRD-A09722536 HA1E 20 uM 6 h -0.28 -1.15 0.44 0.23 0.82 0.1
53275 BRD-A09722536 MCF10A 12 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
87319 BRD-A09722536 BJAB 0.01 uM 6 h 0.0 0.0 0.0 -0.37 -1.23 1.28
87344 BRD-A09722536 HBL1 0.66 uM 24 h 0.0 0.0 0.0 0.24 0.86 0.16
87395 BRD-A09722536 K562 0.66 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
87442 BRD-A09722536 KMS34 10 uM 24 h 0.0 0.0 0.0 0.24 0.83 0.12
87517 BRD-A09722536 MINO 0.66 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
87546 BRD-A09722536 NALM6 2.5 uM 24 h 0.0 0.0 0.0 0.33 1.15 0.9
87597 BRD-A09722536 OCILY10 0.01 uM 24 h 0.0 0.0 0.0 -0.38 -1.29 1.57
87646 BRD-A09722536 OCILY19 0.125 uM 24 h 0.0 0.0 0.0 0.29 1.02 0.48
87698 BRD-A09722536 OCILY3 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
87746 BRD-A09722536 SKMEL5 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
87799 BRD-A09722536 THP1 10 uM 3 h -0.28 -1.16 0.46 0.0 0.0 0.0
87845 BRD-A09722536 TMD8 0.04 uM 3 h 0.0 0.0 0.0 0.0 0.0 0.0
91203 BRD-A09722536 HUH7 12.5 uM 72 h 0.0 0.0 0.0 0.0 0.0 0.0
96075 BRD-A09722536 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
117346 BRD-A09722536 A375 0.37 uM 24 h -0.26 -1.1 0.35 0.23 0.81 0.09
117470 BRD-A09722536 HCC515 0.37 uM 24 h 0.19 0.78 0.0 -0.28 -0.94 0.37
117517 BRD-A09722536 HEPG2 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
117560 BRD-A09722536 HT29 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).