CMap Candidate Details

Structure:
CMap ID: C24802
Pert ID: BRD-K70487031
Compound Name: flupentixol
Targets: DRD1; DRD2
MoA: Dopamine receptor antagonist
SMILES: OCCN1CCN(CCC=C2c3ccccc3Sc3ccc(cc23)C(F)(F)F)CC1
InchiKey: NJMYODHXAKYRHW-DVZOWYKESA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
4135 BRD-K70487031 HA1E 10 uM 24 h 0.0 0.0 0.0 0.37 1.31 1.59
4472 BRD-K70487031 HCC515 10 uM 24 h 0.0 0.0 0.0 0.29 1.01 0.45
4713 BRD-K70487031 PC3 10 uM 24 h 0.19 0.78 0.0 0.31 1.1 0.69
5117 BRD-K70487031 VCAP 10 uM 6 h 0.0 0.0 0.0 -0.37 -1.25 1.35
39167 BRD-K70487031 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39480 BRD-K70487031 A549 10 uM 6 h -0.28 -1.16 0.47 0.31 1.1 0.68
39752 BRD-K70487031 ASC 10 uM 24 h -0.25 -1.04 0.21 -0.37 -1.26 1.35
40045 BRD-K70487031 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40312 BRD-K70487031 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40498 BRD-K70487031 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 -0.35 -1.18 1.14
40854 BRD-K70487031 NEU 10 uM 24 h 0.21 0.88 0.01 0.25 0.88 0.18
41169 BRD-K70487031 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41507 BRD-K70487031 SKB 10 uM 24 h 0.17 0.73 0.0 0.3 1.07 0.62
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).