CMap Candidate Details

Structure:
CMap ID: C24836
Pert ID: BRD-K70577657
Compound Name: H-9
Targets: PRKACA
MoA: PKA inhibitor
SMILES: NCCNS(=O)(=O)c1cccc2cnccc12
InchiKey: DCVZSHVZGVWQKV-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
3047 BRD-K70577657 HA1E 10 uM 6 h -0.25 -1.06 0.26 -0.26 -0.89 0.26
3387 BRD-K70577657 HCC515 10 uM 6 h -0.18 -0.76 0.0 0.0 0.0 0.0
3852 BRD-K70577657 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
39481 BRD-K70577657 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40046 BRD-K70577657 HEPG2 10 uM 6 h 0.0 0.0 0.0 -0.24 -0.8 0.11
40313 BRD-K70577657 HT29 10 uM 6 h -0.17 -0.7 0.0 -0.31 -1.04 0.67
40633 BRD-K70577657 MCF??7.00 10 uM 6 h 0.13 0.55 0.0 0.0 0.0 0.0
40855 BRD-K70577657 NEU 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41170 BRD-K70577657 NPC 10 uM 24 h 0.0 0.0 0.0 -0.33 -1.1 0.85
41508 BRD-K70577657 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
96566 BRD-K70577657 PC3 10 uM 24 h -0.28 -1.16 0.45 -0.33 -1.11 0.91
97281 BRD-K70577657 HAP1 0.66 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
97358 BRD-K70577657 A375 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).