CMap Candidate Details

Structure:
CMap ID: C02488
Pert ID: BRD-K00312224
Compound Name: PPT
Targets: ESR1
MoA: Estrogen receptor agonist
SMILES: CCCc1c(nn(c1-c1ccc(O)cc1)-c1ccc(O)cc1)-c1ccc(O)cc1
InchiKey: IOTXSIGGFRQYKW-UHFFFAOYSA-N
Compound Aliases: ppt

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
4180 BRD-K00312224 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
4329 BRD-K00312224 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
4631 BRD-K00312224 PC3 10 uM 24 h 0.0 0.0 0.0 0.39 1.38 2.16
4872 BRD-K00312224 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
44274 BRD-K00312224 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
44656 BRD-K00312224 A549 10 uM 6 h 0.0 0.0 0.0 -0.24 -0.8 0.12
44806 BRD-K00312224 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
45122 BRD-K00312224 HEPG2 10 uM 6 h -0.28 -1.15 0.43 0.26 0.93 0.27
45395 BRD-K00312224 HT29 10 uM 6 h -0.21 -0.86 0.01 0.27 0.97 0.35
45630 BRD-K00312224 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
45924 BRD-K00312224 NPC 10 uM 24 h 0.0 0.0 0.0 -0.21 -0.72 0.04
46243 BRD-K00312224 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
46557 BRD-K00312224 SKB 10 uM 24 h 0.0 0.0 0.0 0.32 1.14 0.86
99948 BRD-K00312224 U2OS 10 uM 6 h 0.0 0.0 0.0 0.29 1.04 0.55
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).