CMap Candidate Details

Structure:
CMap ID: C24902
Pert ID: BRD-K70792160
Compound Name: 10-DEBC
Targets: PIM1
MoA: Akt inhibitor
SMILES: CCN(CC)CCCCN1c2ccccc2Oc2ccc(Cl)cc12
InchiKey: GYBXAGDWMCJZJK-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
9063 BRD-K70792160 A375 25 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
9225 BRD-K70792160 A549 25 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
9492 BRD-K70792160 AGS 25 uM 6 h 0.0 0.0 0.0 -0.28 -0.96 0.42
9797 BRD-K70792160 H1299 25 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10365 BRD-K70792160 HCC515 25 uM 6 h -0.27 -1.12 0.38 0.34 1.19 1.02
10578 BRD-K70792160 HCT116 25 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10836 BRD-K70792160 HEPG2 25 uM 6 h 0.25 1.04 0.14 0.33 1.16 0.9
11117 BRD-K70792160 HT29 25 uM 6 h 0.22 0.9 0.02 0.31 1.1 0.7
11558 BRD-K70792160 NCIH2073 25 uM 6 h 0.0 0.0 0.0 0.37 1.3 1.49
11823 BRD-K70792160 NCIH508 25 uM 6 h 0.0 0.0 0.0 -0.28 -0.96 0.42
12115 BRD-K70792160 NCIH596 25 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12568 BRD-K70792160 PC3 25 uM 24 h 0.0 0.0 0.0 -0.24 -0.82 0.14
12854 BRD-K70792160 SW480 25 uM 6 h 0.0 0.0 0.0 -0.22 -0.74 0.05
13110 BRD-K70792160 THP1 25 uM 6 h 0.0 0.0 0.0 0.27 0.94 0.29
13669 BRD-K70792160 VCAP 25 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
98767 BRD-K70792160 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
98929 BRD-K70792160 NEU 10 uM 24 h 0.24 0.99 0.09 0.3 1.07 0.62
99408 BRD-K70792160 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
121618 BRD-K70792160 HA1E 10 uM 24 h 0.0 0.0 0.0 0.3 1.06 0.59
121650 BRD-K70792160 HELA 10 uM 24 h 0.19 0.8 0.0 0.35 1.23 1.19
121690 BRD-K70792160 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121713 BRD-K70792160 YAPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).