CMap Candidate Details

Structure:
CMap ID: C24937
Pert ID: BRD-K70881766
Compound Name: solanine
Targets: --
MoA: --
SMILES: C[C@H]1[C@H]2[C@H](C[C@H]3[C@@H]4CC=C5C[C@H](CC[C@]5(C)[C@H]4CC[C@]23C)O[C@@H]6O[C@H](CO)[C@H](O)[C@H](O[C@@H]7O[C@H](CO)[C@@H](O)[C@H](O)[C@H]7O)[C@H]6O[C@@H]8O[C@@H](C)[C@H](O)[C@@H](O)[C@H]8O)N9C[C@@H](C)CC[C@H]19
InchiKey: ZGVSETXHNHBTRK-NILDQRQJSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
4244 BRD-K70881766 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
4475 BRD-K70881766 HCC515 10 uM 24 h 0.36 1.49 1.16 0.0 0.0 0.0
4819 BRD-K70881766 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
4956 BRD-K70881766 VCAP 10 uM 24 h 0.0 0.0 0.0 -0.35 -1.18 1.14
44435 BRD-K70881766 A375 10 uM 6 h 0.0 0.0 0.0 0.3 1.06 0.58
44725 BRD-K70881766 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45012 BRD-K70881766 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
45304 BRD-K70881766 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45566 BRD-K70881766 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45713 BRD-K70881766 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
46126 BRD-K70881766 NPC 10 uM 24 h 0.0 0.0 0.0 -0.25 -0.83 0.17
46440 BRD-K70881766 PHH 10 uM 24 h 0.0 0.0 0.0 -0.27 -0.92 0.33
46765 BRD-K70881766 SKB 10 uM 24 h -0.18 -0.73 0.0 -0.36 -1.2 1.2
99410 BRD-K70881766 U2OS 2.22 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).