CMap Candidate Details

Structure:
CMap ID: C24938
Pert ID: BRD-K70883034
Compound Name: nimetazepam
Targets: GABRA1; GABRA2
MoA: GABA receptor agonist
SMILES: CN1c2ccc(cc2C(=NCC1=O)c1ccccc1)[N+]([O-])=O
InchiKey: GWUSZQUVEVMBPI-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
24473 BRD-K70883034 A375 10 uM 6 h 0.0 0.0 0.0 0.38 1.34 1.72
24603 BRD-K70883034 A549 10 uM 24 h 0.25 1.04 0.14 0.0 0.0 0.0
24804 BRD-K70883034 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
24940 BRD-K70883034 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
25039 BRD-K70883034 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
25183 BRD-K70883034 PC3 10 uM 24 h 0.22 0.93 0.05 0.0 0.0 0.0
25531 BRD-K70883034 VCAP 10 uM 6 h 0.0 0.0 0.0 -0.24 -0.82 0.15
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).