CMap Candidate Details

Structure:
CMap ID: C00250
Pert ID: BRD-A09828896
Compound Name: SKF-81297
Targets: DRD1; DRD5
MoA: Dopamine receptor agonist
SMILES: Oc1cc2C(CNCCc2c(Cl)c1O)c1ccccc1
InchiKey: GHWJEDJMOVUXEC-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1478 BRD-A09828896 HA1E 10 uM 24 h 0.0 0.0 0.0 -0.31 -1.04 0.65
1807 BRD-A09828896 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
2315 BRD-A09828896 PC3 10 uM 6 h 0.0 0.0 0.0 -0.33 -1.11 0.9
2726 BRD-A09828896 VCAP 10 uM 6 h -0.2 -0.85 0.01 -0.21 -0.69 0.02
41642 BRD-A09828896 A375 10 uM 6 h 0.0 0.0 0.0 -0.25 -0.85 0.19
41866 BRD-A09828896 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
42170 BRD-A09828896 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
42515 BRD-A09828896 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
42826 BRD-A09828896 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43108 BRD-A09828896 MCF??7.00 10 uM 24 h -0.27 -1.13 0.42 -0.29 -0.97 0.45
43986 BRD-A09828896 SKB 10 uM 24 h -0.24 -0.99 0.13 0.23 0.8 0.08
98105 BRD-A09828896 NPC 10 uM 24 h 0.0 0.0 0.0 0.31 1.11 0.71
98473 BRD-A09828896 NEU 10 uM 6 h -0.29 -1.21 0.58 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).