CMap Candidate Details

Structure:
CMap ID: C25028
Pert ID: BRD-K71164191
Compound Name: KD-023
Targets: ACACA; ACACB
MoA: ACAT inhibitor
SMILES: CCCCCCCCCCCCCCOc1ccc(o1)C(O)=O
InchiKey: CZRCFAOMWRAFIC-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
96766 BRD-K71164191 PC3 10 uM 24 h 0.28 1.17 0.36 0.0 0.0 0.0
126635 BRD-K71164191 A375 1.11 uM 24 h 0.0 0.0 0.0 -0.32 -1.08 0.79
126655 BRD-K71164191 A549 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
126748 BRD-K71164191 HT29 1.11 uM 24 h 0.0 0.0 0.0 -0.35 -1.18 1.14
126851 BRD-K71164191 MCF??7.00 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
126895 BRD-K71164191 MDAMB231 3.33 uM 24 h 0.0 0.0 0.0 0.35 1.24 1.27
126963 BRD-K71164191 THP1 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127001 BRD-K71164191 YAPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134737 BRD-K71164191 HA1E 2.22 uM 24 h -0.22 -0.9 0.05 0.0 0.0 0.0
134772 BRD-K71164191 HEK293 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134801 BRD-K71164191 HELA 0.08 uM 24 h 0.35 1.45 1.12 0.0 0.0 0.0
134877 BRD-K71164191 HUVEC 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134903 BRD-K71164191 JURKAT 0.03 uM 24 h 0.0 0.0 0.0 0.24 0.86 0.15
134932 BRD-K71164191 MCF10A 0.74 uM 24 h -0.22 -0.92 0.06 -0.34 -1.15 1.07
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).