CMap Candidate Details

Structure:
CMap ID: C25113
Pert ID: BRD-K71427192
Compound Name: BRD-K71427192
Targets: XIAP
MoA: XIAP inhibitor
SMILES: CC(C)[C@H](NC(=O)[C@H](C)N)C(=O)N[C@@H](C)C(=O)Nc1cccc2ccccc12
InchiKey: NUXOKPCTWFCPBI-DEYYWGMASA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
29930 BRD-K71427192 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
30238 BRD-K71427192 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
30535 BRD-K71427192 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
30827 BRD-K71427192 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
31118 BRD-K71427192 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
31431 BRD-K71427192 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
31731 BRD-K71427192 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
32065 BRD-K71427192 MCF??7.00 10 uM 6 h 0.31 1.31 0.78 -0.33 -1.12 0.95
32225 BRD-K71427192 NEU 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
32510 BRD-K71427192 NPC 10 uM 24 h 0.33 1.39 1.02 0.25 0.87 0.17
32672 BRD-K71427192 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
33118 BRD-K71427192 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
33498 BRD-K71427192 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).