CMap Candidate Details

Structure:
CMap ID: C25115
Pert ID: BRD-K71430621
Compound Name: clobenpropit
Targets: HRH3; HRH4
MoA: Histamine receptor antagonist
SMILES: Clc1ccc(CNC(=N)SCCCc2c[nH]cn2)cc1
InchiKey: UCAIEVHKDLMIFL-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1612 BRD-K71430621 HA1E 10 uM 24 h 0.0 0.0 0.0 0.26 0.92 0.25
1957 BRD-K71430621 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
2415 BRD-K71430621 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
24474 BRD-K71430621 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
24605 BRD-K71430621 A549 10 uM 24 h -0.17 -0.7 0.0 -0.26 -0.87 0.23
24941 BRD-K71430621 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
25040 BRD-K71430621 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.31 1.09 0.67
25413 BRD-K71430621 VCAP 10 uM 24 h -0.19 -0.8 0.0 -0.31 -1.05 0.7
42453 BRD-K71430621 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
42765 BRD-K71430621 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43631 BRD-K71430621 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
99417 BRD-K71430621 U2OS 10 uM 6 h 0.0 0.0 0.0 0.17 0.6 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).