CMap Candidate Details
Structure:
| CMap ID: | C25125 |
| Pert ID: | BRD-K71467466 |
| Compound Name: | KPT-185 |
| Targets: | XPO1 |
| MoA: | Exportin antagonist |
| SMILES: | COc1cc(cc(c1)C(F)(F)F)-c1ncn(C=C/C(=O)OC(C)C)n1 |
| InchiKey: | NLNGWFLRRRYNIL-PLNGDYQASA-N |
| Compound Aliases: | -- |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 97017 | BRD-K71467466 | A375 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 97096 | BRD-K71467466 | PC3 | 3.33 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.39 | -1.31 | 1.69 |