CMap Candidate Details

Structure:
CMap ID: C25141
Pert ID: BRD-K71499074
Compound Name: diclofenamide
Targets: CA1; CA2; CA4; CA12
MoA: Carbonic anhydrase inhibitor
SMILES: NS(=O)(=O)c1cc(Cl)c(Cl)c(c1)S(N)(=O)=O
InchiKey: GJQPMPFPNINLKP-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1613 BRD-K71499074 HA1E 10 uM 24 h -0.28 -1.16 0.45 0.0 0.0 0.0
2116 BRD-K71499074 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
2499 BRD-K71499074 VCAP 10 uM 24 h 0.21 0.86 0.01 0.0 0.0 0.0
41833 BRD-K71499074 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
41975 BRD-K71499074 A549 10 uM 24 h -0.24 -1.0 0.15 0.34 1.19 1.03
42454 BRD-K71499074 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
42766 BRD-K71499074 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43064 BRD-K71499074 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43350 BRD-K71499074 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43632 BRD-K71499074 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
43931 BRD-K71499074 PHH 10 uM 24 h 0.0 0.0 0.0 0.29 1.02 0.48
44188 BRD-K71499074 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
52329 BRD-K71499074 PC3 10 uM 24 h 0.0 0.0 0.0 0.28 0.99 0.41
99419 BRD-K71499074 U2OS 6.66 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).