CMap Candidate Details

Structure:
CMap ID: C25157
Pert ID: BRD-K71534238
Compound Name: GW-9508
Targets: FFAR1; FFAR4
MoA: Free fatty acid receptor agonist; G protein-coupled receptor agonist
SMILES: OC(=O)CCc1ccc(NCc2cccc(Oc3ccccc3)c2)cc1
InchiKey: DGENZVKCTGIDRZ-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1958 BRD-K71534238 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
2257 BRD-K71534238 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
2585 BRD-K71534238 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
13854 BRD-K71534238 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
14316 BRD-K71534238 A549 10 uM 6 h 0.0 0.0 0.0 0.23 0.8 0.08
14661 BRD-K71534238 HA1E 10 uM 6 h 0.25 1.03 0.13 0.0 0.0 0.0
15116 BRD-K71534238 HT29 10 uM 24 h 0.0 0.0 0.0 -0.37 -1.24 1.35
42455 BRD-K71534238 ASC 10 uM 24 h 0.0 0.0 0.0 0.22 0.79 0.08
42767 BRD-K71534238 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43229 BRD-K71534238 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
43633 BRD-K71534238 NPC 10 uM 24 h -0.23 -0.97 0.11 0.0 0.0 0.0
43932 BRD-K71534238 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
99420 BRD-K71534238 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).